Brixadi Treatment on Long Island
Brixadi is a long-acting form of buprenorphine given as a weekly or monthly injection to treat opioid use disorder. It offers steady medication levels without daily dosing, and is one of several options within Brixadi and other medication-assisted treatment (MAT) options.
FDA Approved
Extended-release buprenorphine
Weekly or Monthly
Flexible dosing schedule
Provider Administered
No daily home dosing
Insurance Accepted
Medicaid, Medicare & most plans
What Is Brixadi?
Brixadi is an extended-release formulation of buprenorphine, a partial opioid agonist used to treat opioid use disorder. It is injected under the skin by a healthcare provider and slowly releases medication over the following week or month.
Because the dose is stable and continuous, Brixadi can reduce cravings and withdrawal without the daily routine required by oral buprenorphine such as Suboxone.
Brixadi is typically prescribed as part of a Brixadi and MAT treatment plan that includes counseling, medical monitoring, and care coordination.
How Brixadi Works
Brixadi vs. Sublocade vs. Daily Suboxone
| Feature | Brixadi | Sublocade | Suboxone (oral) |
|---|---|---|---|
| Dosing | Weekly or monthly | Monthly | Daily |
| Administration | Subcutaneous injection by clinician | Subcutaneous abdominal injection | Film or tablet at home |
| Induction speed | Often same-day after test dose | About 7 days on oral buprenorphine first | Same-day induction |
| Injection sites | Abdomen, thigh, buttock, upper arm | Abdomen only | Not applicable |
Who Brixadi May Be Right For
A clinician may consider Brixadi for people who:
Brixadi is also frequently discussed for people recovering from fentanyl and heroin dependence, where careful induction timing matters.
Starting Brixadi Safely
Starting Brixadi while full opioids are still active can cause precipitated withdrawal. Induction must be timed and supervised by a qualified clinician.
For people using fentanyl or high-dose opioids, medical detox on Long Island can help create a stable window for safe induction.
Insurance and Cost on Long Island
Most commercial plans, New York Medicaid, and Medicare cover Brixadi, though prior authorization is common. Manufacturer copay assistance may reduce out-of-pocket costs for eligible patients.
We verify coverage at no cost and identify prescribers with real availability across Nassau County and Suffolk County.
Brixadi Alongside Other Levels of Care
Brixadi is often combined with counseling and structured care as part of a complete Brixadi and MAT program.
Outpatient
Regular clinic visits for injections and counseling.
Outpatient programsIOP with MAT
Structured therapy combined with Brixadi maintenance.
IOP programsInpatient
Residential care with medication and clinical support.
Inpatient rehabFrequently Asked Questions
Learn More About Brixadi Options on Long Island
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Medical References & Sources
This page contains information sourced from peer-reviewed medical literature, federal health agencies, and accredited medical institutions to ensure accuracy and compliance with E-E-A-T (Experience, Expertise, Authoritativeness, and Trustworthiness) standards.
- Substance Abuse and Mental Health Services Administration (SAMHSA). "Medications for Opioid Use Disorder (TIP 63)." Treatment Improvement Protocol Series, 2021. Available at: https://store.samhsa.gov/product/tip-63-medications-opioid-use-disorder/PEP21-02-01-002
- National Institute on Drug Abuse (NIDA). "Medications to Treat Opioid Use Disorder Research Report." National Institutes of Health, 2024. Available at: https://nida.nih.gov/publications/research-reports/medications-to-treat-opioid-addiction
- U.S. Food and Drug Administration (FDA). "Brixadi (buprenorphine) extended-release injection prescribing information." FDA, 2023. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/217136s000lbl.pdf
- New York State Office of Addiction Services and Supports (OASAS). "Medication-Assisted Treatment Programs." OASAS, 2024. Available at: https://oasas.ny.gov/providers
Medical Disclaimer
The information provided on this page is for educational purposes only and should not be considered medical advice. This page does not provide medical diagnoses, treatment prescriptions, or clinical recommendations. Always consult with qualified healthcare professionals for diagnosis and treatment of substance use disorders. If you are experiencing a medical emergency, call 911 immediately.
This content was written by certified addiction professionals and reviewed by licensed medical practitioners to ensure accuracy and adherence to current clinical guidelines. Last fact-checked: August 21, 2026.
If you or someone you know is struggling with substance use, you can reach our 24/7 confidential Long Island Rehab Helpline at 844-338-6969 for free, confidential information and treatment referral.
Medical disclaimer: This page is educational and is not medical advice. Treatment decisions about Brixadi or any medication should be made with a licensed clinician who can evaluate your individual history and needs.