Naloxone saves lives by rapidly reversing opioid overdoses. Learn how it works, how to use it, and where to get it free in New York.
Naloxone (brand name Narcan) is a medication that rapidly reverses the effects of opioid overdose. It works on all opioids, including heroin,fentanyl, oxycodone, hydrocodone, and other prescription and illicit opioids.
Naloxone has been used in emergency medicine since 1971 and has saved countless lives. Today, it's available in easy-to-use nasal spray and injectable forms that anyone can administer—no medical training required.
The medication is an "opioid antagonist," meaning it binds to opioid receptors in the brain without activating them. By occupying these receptors, it blocks opioids and reverses their dangerous effects, particularly respiratory depression (slowed or stopped breathing).
Knowing the signs of opioid overdose can save a life. Look for these warning signs:
| Form | Brand Names | How to Use | Notes |
|---|---|---|---|
| Nasal Spray | Narcan, Kloxxado | Spray into one nostril | Easiest to use, no assembly |
| Auto-injector | Evzio | Press against thigh, auto-injects | Voice instructions guide you |
| Injectable | Generic naloxone | Draw into syringe, inject into muscle | Requires some training |
In New York State, naloxone is available without a prescription. Here's where you can get it:
Most pharmacies carry naloxone and can dispense it without a prescription. Some offer it free; otherwise, most insurance covers it.
Local harm reduction organizations provide free naloxone and training. Check with your county health department for locations.
Federally Qualified Health Centers often provide free naloxone to community members regardless of patient status.
Get free Narcan and other harm reduction supplies for NY residents through our partner organizations.
Learn more →New York's Good Samaritan Law protects people who call 911 or administer naloxone during an overdose emergency. Under this law:
Don't let fear of legal consequences stop you from saving a life. The law is designed to encourage people to seek help during overdose emergencies.
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Call 631-762-3763This page contains information sourced from peer-reviewed medical literature, federal health agencies, and accredited medical institutions to ensure accuracy and compliance with E-E-A-T (Experience, Expertise, Authoritativeness, and Trustworthiness) standards.
The information provided on this page is for educational purposes only and should not be considered medical advice. This page does not provide medical diagnoses, treatment prescriptions, or clinical recommendations. Always consult with qualified healthcare professionals for diagnosis and treatment of substance use disorders. If you are experiencing a medical emergency, call 911 immediately.
This content was written by certified addiction professionals and reviewed by licensed medical practitioners to ensure accuracy and adherence to current clinical guidelines. Last fact-checked: July 11, 2026.
If you or someone you know is struggling with substance use, you can reach our 24/7 confidential Long Island Rehab Helpline at 631-762-3763 for free, confidential information and treatment referral.